Chiral Silanols: Strategies and Tactics for Their Synthesis
Jihui Gao, Chuan He
Abstract
Silanols are valuable and important compounds, which have found widespread applications in the field of materials science, synthetic chemistry, and medicinal chemistry. Although a handful of approaches have been developed for the synthesis of various silanols, access to enantioenriched silicon-stereogenic silanols remains underdeveloped. This Concept article intends to summarize and highlight recent advances in the construction of silicon-stereogenic silanols and endeavors to encourage further research in this area.
Topics & Concepts
StereocenterChemistryEngineering ethicsNanotechnologyEnantioselective synthesisOrganic chemistryEngineeringCatalysisMaterials scienceOrganoboron and organosilicon chemistrySynthetic Organic Chemistry MethodsSynthesis and characterization of novel inorganic/organometallic compounds