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Mild and Selective Rhodium-Catalyzed Transfer Hydrogenation of Functionalized Arenes

Yuhan Wang, Zhiqian Chang, Yan Hu, Xiao Lin, Xiaowei Dou

2021Organic Letters27 citationsDOI

Abstract

Diboron-mediated rhodium-catalyzed transfer hydrogenation of functionalized arenes is reported. In addition to good functional group tolerance, the reaction features operational simplicity and controllable chemoselectivity. The general applicability of this procedure is demonstrated by the selective hydrogenation of a range of arenes, including functionalized benzenes, biphenyls, and polyaromatics.

Topics & Concepts

ChemoselectivityRhodiumChemistryCatalysisTransfer hydrogenationFunctional groupCombinatorial chemistrySimplicityOrganic chemistryReaction conditionsPhilosophyPolymerEpistemologyRutheniumAsymmetric Hydrogenation and CatalysisOrganoboron and organosilicon chemistryCatalytic C–H Functionalization Methods
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