5-Fluorouracil-loaded chitosan nanoparticles conjugated with methotrexate for targeted therapy of colorectal cancer
Aline Martins dos Santos, Raquel Bester Liszbinski, Suzana Gonçalves Carvalho, Alberto Gomes Tavares, Marlus Chorilli, Marcelo Bispo de Jesus, Maria Palmira Daflon Gremião
Topics & Concepts
Conjugated systemMethotrexateColorectal cancerFourier transform infrared spectroscopyFluorouracilCancer researchTargeted therapyChitosanConjugateTargeted drug deliveryDrug deliveryMetastasisCovalent bondNanoparticleChemistryMedicineCancerOncologyMaterials scienceInternal medicineNanotechnologyPolymerBiochemistryChemical engineeringOrganic chemistryEngineeringMathematicsMathematical analysisNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsHER2/EGFR in Cancer Research