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Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans

Margherita Ortalli, Stefania Varani, Giorgia Cimato, Ruben Veronesi, Arianna Quintavalla, Marco Lombardo, Magda Monari, Claudio Trombini

2020Journal of Medicinal Chemistry16 citationsDOIOpen Access PDF

Abstract

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Topics & Concepts

ChemistryAmastigoteTetrahydropyranLeishmaniaLeishmania donovaniCombinatorial chemistryStereochemistryIn vitroBiochemistryOrganic chemistryRing (chemistry)World Wide WebParasite hostingComputer scienceResearch on Leishmaniasis StudiesTrypanosoma species research and implicationsInsect Pest Control Strategies
Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans | Litcius