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Expression of two glutamate decarboxylase genes in <i>Lactobacillus brevis</i> during gamma-aminobutyric acid production with date residue extract

Momoko Hasegawa, Sotaro Fujii, Kouichi Funato, Atsushi Yoshida, Yoshihiro Sambongi

2020Bioscience Biotechnology and Biochemistry12 citationsDOI

Abstract

Abstract Gamma-aminobutyric acid (GABA) is produced by Lactobacillus brevis using date residue fermentation. In this study, the GABA production method was improved, for which L. brevis strain JCM 1059T was the most efficient among the four L. brevis strains examined. This was presumably due to a difference in the expression level of the gene encoding glutamate decarboxylase that catalyzes GABA synthesis. Abbreviation GABA: gamma-aminobutyric acid

Topics & Concepts

Lactobacillus brevisGlutamate decarboxylaseFermentationgamma-Aminobutyric acidResidue (chemistry)BiochemistryGlutamate receptorChemistryGeneEnzymeCarboxy-lyasesBiologyBacteriaLactic acidGeneticsLactobacillus plantarumReceptorGABA and Rice ResearchMedicinal Plants and NeuroprotectionProbiotics and Fermented Foods
Expression of two glutamate decarboxylase genes in <i>Lactobacillus brevis</i> during gamma-aminobutyric acid production with date residue extract | Litcius