Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus
So Jin Bing, Morten Seirup, Trish T. Hoang, Susana S. Najera, Collin Britten, Stephanee Warrington, S Chu, Ronit Mazor
Topics & Concepts
EpitopeCapsidImmunogenicityBiologyVirologyAdeno-associated virusTransduction (biophysics)Epitope mappingMajor histocompatibility complexMolecular biologyVirusImmune systemGeneRecombinant DNAAntigenVector (molecular biology)GeneticsBiochemistryVirus-based gene therapy researchCAR-T cell therapy researchViral Infectious Diseases and Gene Expression in Insects