Western diet induces GSDME-mediated epithelial pyroptosis through the DCA-S1PR2 pathway to disrupt the intestinal epithelial barrier
Ke Liu, Mengyao Song, Xueqin Huang, Yanqiang Shi, Sheng Li, Fangqing Zhu, Teng Ben, Xinlong Lin, Bingxia Chen, Beibei Xu, Sicong Ma, Binhai Shen, Zheng Chen, Xinwen Yan, Ruo Huang, Fachao Zhi, Gao Tan
Topics & Concepts
PyroptosisCell biologyChemistryEpitheliumOccludinTight junctionApoptosisBiologyProgrammed cell deathBiochemistryGeneticsInflammasome and immune disordersEosinophilic EsophagitisIL-33, ST2, and ILC Pathways