Tryptophan Oxidation of a Monoclonal Antibody Under Diverse Oxidative Stress Conditions: Distinct Oxidative Pathways Favor Specific Tryptophan Residues
Alex W. Jacobitz, Qian Liu, Sreekanth Suravajjala, Neeraj J. Agrawal
Topics & Concepts
TryptophanChemistryMonoclonal antibodyOxidative stressResidue (chemistry)Oxidative phosphorylationBiochemistryAntibodyAmino acidBiologyImmunologyMonoclonal and Polyclonal Antibodies ResearchProtein purification and stabilityT-cell and B-cell Immunology