Quinoline alkaloids with anti-inflammatory activity from <i>Zanthoxylum avicennae</i>
Kai‐Long Ji, Wei Liu, Wei-Hang Yin, Jing-Ya Li, Jian‐Min Yue
Abstract
]furan moiety. The putative biosynthetic pathway for enantiomeric compounds was also proposed. In addition, compound 6 significantly suppressed the gene expression and secretion of pro-inflammatory cytokines IL-1β and IL-6 in macrophages.
Topics & Concepts
QuinolineZanthoxylumChemistryRutaceaeAlkaloidTraditional medicineStereochemistryBiologyOrganic chemistryMedicineBotanyBioactive Compounds and Antitumor AgentsPlant chemical constituents analysisPhenothiazines and Benzothiazines Synthesis and Activities