Clinical Implications of an Acute Dip in eGFR after SGLT2 Inhibitor Initiation
Hiddo J.L. Heerspink, David Z.I. Cherney
Abstract
Glomerular hyperfiltration is one of the earliest mechanisms contributing to CKD initiation and progression. Experimental and clinical studies have shown glomerular hyperfiltration is associated with kidney injury in many CKD etiologies, and is a consequence of complex interactions between growth
Topics & Concepts
MedicineGlomerular hyperfiltrationRenal functionAcute kidney injuryEtiologyUrologyInternal medicineIntensive care medicineKidneyDiabetic nephropathyDiabetes Treatment and ManagementChronic Kidney Disease and DiabetesElectrolyte and hormonal disorders