Activated Platelets, the Booster of Chronic Kidney Disease and Cardiovascular Complications
Shuiqin Gong, Chenyu Wang, Jiachuan Xiong, Jinghong Zhao, Ke Yang
Abstract
Background Chronic kidney disease (CKD) has become a global public health problem nowadays. As cardiovascular diseases (CVDs) are the primary cause of death in advanced CKD patients, much attention has been paid to resolving their cardiovascular complications. However, managing CKD and cardiovascular complications is still a big challenge for nephrologists, as satisfactory treatments are still lacking. Platelets, the second most abundant cells in the blood, are the major participants of hemostasis, thrombosis, and wound healing. In recent years, platelets have been reported in various physiological and pathological processes, including CKD and CKD-related CVDs.
Topics & Concepts
MedicineKidney diseasePlateletHemostasisDiseaseThrombosisInternal medicinePathologicalPlatelet activationIntensive care medicinePlatelet Disorders and TreatmentsBlood properties and coagulationSexual function and dysfunction studies