Tubeimoside-I, an inhibitor of HSPD1, enhances cytotoxicity of oxaliplatin by activating ER stress and MAPK signaling pathways in colorectal cancer
Tao Wu, Yun Yu, Xinyue Tu, Lihua Ye, Jiaying Wang, Chenjun Xie, Keke Kuang, Yingyan Yu, Weishan Zhuge, Zhong Lin Wang, Ri Cui, Yihu Zheng
Topics & Concepts
OxaliplatinColorectal cancerReactive oxygen speciesCytotoxicityMAPK/ERK pathwayCancerMedicineProgrammed cell deathSignal transductionCancer researchPharmacologyApoptosisChemistryBiologyInternal medicineCell biologyBiochemistryIn vitroNatural product bioactivities and synthesisPlant-derived Lignans Synthesis and BioactivitySesquiterpenes and Asteraceae Studies