Litcius/Paper detail

Recent Advances on Quinazoline Derivatives: A Potential Bioactive Scaffold in Medicinal Chemistry

Ram Karan, Pooja Agarwal, Mukty Sinha, Neelima Mahato

2021ChemEngineering94 citationsDOIOpen Access PDF

Abstract

This paper intended to explore and discover recent therapeutic agents in the area of medicinal chemistry for the treatment of various diseases. Heterocyclic compounds represent an important group of biologically active compounds. In the last few years, heterocyclic compounds having quinazoline moiety have drawn immense attention owing to their significant biological activities. A diverse range of molecules having quinazoline moiety are reported to show a broad range of medicinal activities like antifungal, antiviral, antidiabetic, anticancer, anti-inflammatory, antibacterial, antioxidant and other activities. This study accelerates the designing process to generate a greater number of biologically active candidates.

Topics & Concepts

AntifungalQuinazolineMoietyChemistryCombinatorial chemistryBiological activityOrganic chemistryBiochemistryBiologyIn vitroMicrobiologyQuinazolinone synthesis and applicationsSynthesis and biological activityMulticomponent Synthesis of Heterocycles
Recent Advances on Quinazoline Derivatives: A Potential Bioactive Scaffold in Medicinal Chemistry | Litcius