STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway
Jie Zhao, Xin Liu, Yao Chen, Linshuang Zhang, Ya-Rong Zhang, Deng-Ren Ji, Shi‐Meng Liu, Mo-Zhi Jia, Yonghong Zhu, Yongfen Qi, Fengmin Lu, Yan-Rong Yu
Abstract
Schistosomiasis is a parasitic helminth disease that can cause organ lesions leading to health damage. During a schistosome infection, schistosome eggs can flow into the liver along the portal vein.
Topics & Concepts
BiologySchistosomiasisInflammationOxidative stressApoptosisSTAT3Liver injurySchistosoma japonicumImmunologySignal transductionSchistosomaHelminthiasisCancer researchHelminthsCell biologySchistosoma mansoniEndocrinologyBiochemistryParasites and Host InteractionsLiver Disease and TransplantationMacrophage Migration Inhibitory Factor