CRL2APPBP2-mediated TSPYL2 degradation counteracts human mesenchymal stem cell senescence
Daoyuan Huang, Qian Zhao, Kuan Yang, Jinghui Lei, Ying Jing, Hongyu Li, Chen Zhang, Shuai Ma, Shuhui Sun, Yusheng Cai, Guibin Wang, Jing Qu, Weiqi Zhang, Si Wang, Guang‐Hui Liu
Topics & Concepts
CullinSenescenceCell biologyUbiquitinBiologyProteostasisProteasomeMesenchymal stem cellProgeriaUbiquitin ligaseProtein degradationEmbryonic stem cellGeneticsGeneUbiquitin and proteasome pathwaysGenetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation