Development of a peptide-based lateral flow assay for the detection of the cancer biomarker Mdm2
Bryan Gosselin, Maurice Retout, Ivan Jabin, Gilles Bruylants
Abstract
This study explores the use of peptide aptamers as effective recognition units in lateral flow assays, comparing two immobilization strategies on test line. Peptide aptamers show superior performance and ease of use compared to classical antibodies.
Topics & Concepts
AptamerPeptideBiomarkerCancer researchComputational biologyChemistryBiologyMolecular biologyBiochemistryAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionAdvanced Biosensing Techniques and Applications