Performance of Conventional Urine Culture Compared to 16S rRNA Gene Amplicon Sequencing in Children with Suspected Urinary Tract Infection
C. W. Marshall, Marcia Kurs‐Lasky, Christi L. McElheny, Sophia Bridwell, Hui Liu, Nader Shaikh
Abstract
Concordance between conventional culture and 16S rRNA gene amplicon sequencing appears to be high. In children with equivocal culture results, 16S rRNA gene results may provide information that may help clarify the diagnosis.
Topics & Concepts
Urinary systemAmplicon16S ribosomal RNAAmplicon sequencingUrineBiologyGeneRibosomal RNAGeneticsPolymerase chain reactionMicrobiologyEndocrinologyPediatric Urology and Nephrology StudiesUrinary Tract Infections ManagementBladder and Urothelial Cancer Treatments