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Berberine-mediated REDD1 down-regulation ameliorates senescence of retinal pigment epithelium by interrupting the ROS-DDR positive feedback loop

Qingqiu Chen, Guang Xin, Shiyi Li, Yuman Dong, Xiuxian Yu, Chengyu Wan, Zeliang Wei, Yuda Zhu, Kun Zhang, Yilan Wang, Fan Li, Cuicui Zhang, E Wen, Yulong Li, Hai Niu, Wen Huang

2022Phytomedicine36 citationsDOI

Topics & Concepts

SenescenceReactive oxygen speciesOxidative stressBerberineCell biologyRetinal pigment epitheliumRetinalChemistryBiologyPharmacologyBiochemistryBerberine and alkaloids researchAntioxidants, Aging, Portulaca oleraceaRetinal Diseases and Treatments
Berberine-mediated REDD1 down-regulation ameliorates senescence of retinal pigment epithelium by interrupting the ROS-DDR positive feedback loop | Litcius