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Discovery of novel (E)-1-methyl-9-(3-methylbenzylidene)-6,7,8,9-tetrahydropyrazolo[3,4-d]pyrido[1,2-a]pyrimidin-4(1H)-one as DDR2 kinase inhibitor: Synthesis, molecular docking, and anticancer properties

Zukela Ruzi, Khurshed Bozorov, Lifei Nie, Jiangyu Zhao, Haji Akber Aisa

2023Bioorganic Chemistry15 citationsDOI

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ChemistryCell growthCell cycleCell cultureCell cycle checkpointKinaseApoptosisDocking (animal)Cancer cellMolecular biologyCell biologyBiochemistryCancerBiologyGeneticsNursingMedicineSynthesis and biological activityQuinazolinone synthesis and applicationsCancer therapeutics and mechanisms
Discovery of novel (E)-1-methyl-9-(3-methylbenzylidene)-6,7,8,9-tetrahydropyrazolo[3,4-d]pyrido[1,2-a]pyrimidin-4(1H)-one as DDR2 kinase inhibitor: Synthesis, molecular docking, and anticancer properties | Litcius