Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma
Mark W. Zimmerman, Adam D. Durbin, Shuning He, Felix Oppel, Hui Shi, Ting Tao, Zhaodong Li, Alla Berezovskaya, Yu Liu, Jinghui Zhang, Richard A. Young, Brian J. Abraham, A. Thomas Look
Abstract
Retinoic acid reprograms neuroblastoma cell identity by remodeling the core transcriptional regulatory circuitry.
Topics & Concepts
Retinoic acidNeuroblastomaAdrenergicCore (optical fiber)TretinoinMedicineInternal medicineEndocrinologyNeuroscienceBiologyComputer scienceGeneticsReceptorTelecommunicationsGeneCell cultureNeuroblastoma Research and TreatmentsProtein Degradation and Inhibitorsinterferon and immune responses