Al centre-powered graphitic nanozyme with high catalytic efficiency for pH-independent chemodynamic therapy of cancer
Jun Li, Ke Yi, Yanli Lei, Zhihe Qing, Zhen Zou, Yuedong Zhang, Haiyan Sun, Ronghua Yang
Abstract
An Al centre-powered graphitic nanozyme derived from a metal organic framework was first developed for a chemodynamic tumor treatment. By virtue of the rapid and efficient generation of ˙OH in the slightly acidic tumor microenvironment, this nanozyme afforded high anti-tumor efficacy both in living cells and in vivo.
Topics & Concepts
CatalysisKineticsChemistryCancer therapyCancerBiochemistryMedicineInternal medicineQuantum mechanicsPhysicsAdvanced Nanomaterials in CatalysisNanoplatforms for cancer theranosticsNanocluster Synthesis and Applications