Litcius/Paper detail

Hydrophobic and polar interactions of FDA-approved small molecule protein kinase inhibitors with their target enzymes

Robert Roskoski

2021Pharmacological Research37 citationsDOI

Topics & Concepts

Allosteric regulationSmall moleculeChemistryBiochemistryKinaseDrug discoveryProtein kinase AEnzymeBinding siteProtein Kinase Regulation and GTPase SignalingMelanoma and MAPK PathwaysQuinazolinone synthesis and applications
Hydrophobic and polar interactions of FDA-approved small molecule protein kinase inhibitors with their target enzymes | Litcius