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Levo-tetrahydropalmatine ameliorates neuropathic pain by inhibiting the activation of the Clec7a-MAPK/NF-κB-NLRP3 inflammasome axis

Dan Wu, Ping Wang, Chunhui Zhao, Jin Su, Junhong Zhang, Wangming Ma, Yanqiong Zhang, Haiyu Xu

2023Phytomedicine35 citationsDOI

Topics & Concepts

Neuropathic painMAPK/ERK pathwayPharmacologyInflammasomeNeuroinflammationPyroptosisTHP1 cell lineNF-κBMedicineSignal transductionChemistryInflammationBiologyBiochemistryImmunologyCell cultureGeneticsPain Mechanisms and TreatmentsAdenosine and Purinergic SignalingMuscle Physiology and Disorders
Levo-tetrahydropalmatine ameliorates neuropathic pain by inhibiting the activation of the Clec7a-MAPK/NF-κB-NLRP3 inflammasome axis | Litcius