IRE1α-XBP1 regulates PDK1-dependent induction of epithelial-mesenchymal transition in non-small cell lung cancer cells
Xike Mao, Chenxi Yu, Feng Yin, Wenjiao Xu, Yonghan Pan, Bowen Yang, Tao Huang, Siling Chen, Wenge Luo, Tianyu Su, Zhihao Wu
Topics & Concepts
Unfolded protein responseBiologyXBP1Cancer cellCell biologyPyruvate kinaseWarburg effectGlycolysisDownregulation and upregulationCancer researchCancerBiochemistryEndoplasmic reticulumMetabolismGeneticsRNAGeneRNA splicingEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyAdipose Tissue and Metabolism