Advances in Hypothermic and Normothermic Perfusion in Kidney Transplantation
Thomas B. Smith, Michael L. Nicholson, Sarah A. Hosgood
Abstract
Hypothermic and normothermic machine perfusion in kidney transplantation are purported to exert a beneficial effect on post-transplant outcomes compared to the traditionally used method of static cold storage. Kidney perfusion techniques provide a window for organ reconditioning and quality assessment. However, how best to deliver these preservation methods or improve organ quality has not yet been conclusively defined. This review summarises the promising advances in machine perfusion science in recent years, which have the potential to further improve early graft function and prolong graft survival.
Topics & Concepts
Machine perfusionPerfusionMedicineKidney transplantationTransplantationKidneyCold storageIntensive care medicineSurgeryCardiologyInternal medicineBiologyHorticultureLiver transplantationOrgan Transplantation Techniques and OutcomesLiver Disease and TransplantationRenal Transplantation Outcomes and Treatments