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Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity

Gillian Houlihan, Sebastian Arangundy‐Franklin, Benjamin T. Porebski, Nithya Subramanian, Alexander I. Taylor, Philipp Holliger

2020Nature Chemistry64 citationsDOIOpen Access PDF

Topics & Concepts

Nucleic acidRNAProofreadingChemistryDNAReverse transcriptaseDirected evolutionComputational biologyNucleic acid structureBiochemistryPolymeraseBiologyGeneMutantDNA and Nucleic Acid ChemistryRNA and protein synthesis mechanismsAdvanced biosensing and bioanalysis techniques
Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity | Litcius