AIE-based gold nanostar-berberine dimer nanocomposites for PDT and PTT combination therapy toward breast cancer
Rong-Tian Li, Ming Chen, Zi-Chuan Yang, Yongjian Chen, Nai-Han Huang, Wen‐Hua Chen, Jun Chen, Jin-Xiang Chen
Abstract
We have developed a series of berberine-based dimers with notable AIE properties to interact with pre-designed gold nanostar to achieve synergistic treatment amongst chemo- and photothermal- and photodynamic therapies for breast cancer.
Topics & Concepts
BerberinePhotodynamic therapySinglet oxygenChemistryIn vivoCancer cellHyaluronic acidNanocarriersPhotothermal therapyCombinatorial chemistryCancerNanotechnologyMaterials scienceDrug deliveryOrganic chemistryMedicineBiologyAnatomyBiotechnologyInternal medicineOxygenNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsNicotinic Acetylcholine Receptors Study