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Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival

Ruiying Hu, Emily M. Walker, Chen Huang, Yanwen Xu, Chen Weng, Gillian E. Erickson, Anastasia Coldren, Xiaodun Yang, Marcela Briššová, Irina Kaverina, Appakalai N. Balamurugan, Christopher V.E. Wright, Yan Li, Roland Stein, Guoqiang Gu

2020Developmental Cell25 citationsDOIOpen Access PDF

Topics & Concepts

BiologyATF4Gene knockdownTranscription factorCellular stress responseCell biologyDownregulation and upregulationHeat shock proteinEffectorUnfolded protein responseGeneCancer researchGeneticsFight-or-flight responsePancreatic function and diabetesEndoplasmic Reticulum Stress and DiseaseGenetics and Neurodevelopmental Disorders
Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival | Litcius