Thermoresponsive Liposomes for Photo-Triggered Release of Hypericin Cyclodextrin Inclusion Complex for Efficient Antimicrobial Photodynamic Therapy
Alice Abu Dayyih, Bernd Gutberlet, Eduard Preis, Konrad Engelhardt, Muhammad Umair Amin, Ahmed M. Abdelsalam, Martina Bonsu, Udo Bakowsky
Abstract
), indicating that the NIR-activated TSL have immense therapeutic potential to enhance the antibacterial efficacy. The liposomes showed good biocompatibility, which was confirmed by the cellular viability of mouse fibroblasts (L929).
Topics & Concepts
LiposomePhotothermal therapyBiocompatibilitySinglet oxygenHypericinCyclodextrinPhotodynamic therapyPhotosensitizerViability assayAntimicrobialMaterials sciencePermeationReactive oxygen speciesBiophysicsMembraneNuclear chemistryChemistryNanotechnologyOxygenPhotochemistryBiochemistryApoptosisPharmacologyOrganic chemistryBiologyMetallurgyNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesPolydiacetylene-based materials and applications