SCD1 promotes the stemness of gastric cancer stem cells by inhibiting ferroptosis through the SQLE/cholesterol/mTOR signalling pathway
Xinyuan Mao, Lingzhi Wang, Zhian Chen, Huilin Huang, Jialin Chen, Jin Su, Zhenhao Li, Guodong Shen, Yingxin Ren, Zhenyuan Li, Weisheng Wang, Jinzhou Ou, Weihong Guo, Yanfeng Hu
Topics & Concepts
Squalene monooxygenaseGene knockdownCancer researchCancerCancer stem cellPI3K/AKT/mTOR pathwayCancer cellChemistryBiologyStem cellCell biologySignal transductionApoptosisBiochemistryGeneGeneticsBiosynthesisFerroptosis and cancer prognosisCancer, Lipids, and MetabolismRNA modifications and cancer