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Design, synthesis and biological evaluation of novel 5-(4-chlorophenyl)-4-phenyl-4H-1,2,4-triazole-3-thiols as an anticancer agent

Krupa R. Patel, Jpan Brahmbhatt, Pranav A. Pandya, Drashti G. Daraji, Hitesh D. Patel, Rakesh Rawal, Sujit K. Baran

2021Journal of Molecular Structure27 citationsDOI

Topics & Concepts

ChemistryIn silicoIn vitroTriazoleCombinatorial chemistryClick chemistryLead compoundHL60Cell cultureIC50A549 cellThiolStructure–activity relationshipStereochemistryBiochemistryOrganic chemistryGeneticsBiologyGeneClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic CompoundsCancer-related Molecular Pathways
Design, synthesis and biological evaluation of novel 5-(4-chlorophenyl)-4-phenyl-4H-1,2,4-triazole-3-thiols as an anticancer agent | Litcius