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The normalized limit of detection in NMR spectroscopy

Piotr Lepucki, A. P. Dioguardi, Daniil Karnaushenko, Oliver G. Schmidt, H.‐J. Grafe

2021Journal of Magnetic Resonance22 citationsDOIOpen Access PDF

Abstract

We derive the normalized limit of detection for frequency space (nLODf) as a parameter to measure the sensitivity of an NMR spectroscopy setup. nLODf is independent of measurement settings such as bandwidth or number of measurement points, and allows to compare performances of different setups. We demonstrate the usefulness of the new nLODf by comparing the sensitivity of NMR setups from various publications, which all use microcoils. Finally, we want to propose a standard measurement and report format for the sensitivity of new NMR setups.

Topics & Concepts

Sensitivity (control systems)Detection limitNuclear magnetic resonance spectroscopySpectroscopyLimit (mathematics)Measure (data warehouse)Transverse relaxation-optimized spectroscopyBandwidth (computing)Analytical Chemistry (journal)Computational physicsNuclear magnetic resonanceMaterials sciencePhysicsChemistryComputer scienceFluorine-19 NMRMathematicsElectronic engineeringChromatographyData miningMathematical analysisTelecommunicationsEngineeringQuantum mechanicsNMR spectroscopy and applicationsAdvanced MRI Techniques and ApplicationsAtomic and Subatomic Physics Research
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