Litcius/Paper detail

Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

David A. Braun, Yue Hou, Ziad Bakouny, Miriam Ficial, Miriam Sant’ Angelo, Juliet Forman, Petra Ross‐Macdonald, Ashton C. Berger, Opeyemi A. Jegede, Liudmilla Elagina, John A. Steinharter, Maxine Sun, Megan Wind‐Rotolo, Jean‐Christophe Pignon, Andrew D. Cherniack, Lee Lichtenstein, Donna Neuberg, Paul Catalano, Gordon J. Freeman, Arlene H. Sharpe, David F. McDermott, Eliezer M. Van Allen, Sabina Signoretti, Catherine J. Wu, Sachet A. Shukla, Toni K. Choueiri

2020Nature Medicine1,026 citationsDOIOpen Access PDF

Topics & Concepts

BlockadeImmune checkpointCancer researchSomatic cellPD-L1ImmunotherapyClear cell renal cell carcinomaImmune systemCD8Renal cell carcinomaBiologyMedicineImmunologyPathologyInternal medicineGeneticsReceptorGeneRenal cell carcinoma treatmentCancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics
Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma | Litcius