Impaired CaV1.2 inactivation reduces the efficacy of calcium channel blockers in the treatment of LQT8
Moradeke A. Bamgboye, Maria K. Traficante, Josiah O. Owoyemi, Deborah DiSilvestre, Daiana C.O. Vieira, Ivy E. Dick
Topics & Concepts
VerapamilCalcium channelLong QT syndromeCav1.2MutationPopulationPharmacologyVoltage-dependent calcium channelInduced pluripotent stem cellMedicineCalciumBiologyGeneticsInternal medicineGeneQT intervalEmbryonic stem cellEnvironmental healthCardiac electrophysiology and arrhythmiasIon channel regulation and functionReceptor Mechanisms and Signaling