Strategies for assessing the limit of detection in voltammetric methods: comparison and evaluation of approaches
Colby E. Ott
Abstract
two common voltammetry methods: cyclic voltammetry and square-wave voltammetry. The LOD for each analyte was estimated and/or calculated following a variety of literature-described methods and compared. The accuracy and reliability of these LOD characteristics based on the experimental data is described herein along with suggestions and recommendations. This manuscript is intended to compare the resulting LOD values from various methods and provide a starting point for the incorporation of electrochemistry into the forensic science laboratory, beginning a focused discussion on the development of validation guidelines and parameters needed for the adoption of this technology in forensic laboratories in order to meet the standards required by the criminal justice system.