Mechanism and inhibition of BRAF kinase
Amber Gunderwala, Nicholas Cope, Zhihong Wang
Topics & Concepts
KinaseMechanism (biology)MAPK/ERK pathwayCancer researchMutantProtein kinase domainSmall moleculeDrug discoveryComputational biologyBiologyCell biologyChemistryBioinformaticsBiochemistryGenePhilosophyEpistemologyMelanoma and MAPK PathwaysProtein Kinase Regulation and GTPase SignalingCytokine Signaling Pathways and Interactions