Non-motor symptoms in amyotrophic lateral sclerosis: lessons from Parkinson’s disease
Ali Shojaie, Silvia Rota, Ahmad Al Khleifat, К. Ray Chaudhuri, Ammar Al‐Chalabi
Abstract
Amyotrophic lateral sclerosis and Parkinson's disease are neurodegenerative diseases of the motor system which are now recognized also to affect non-motor pathways. Non-motor symptoms have been acknowledged as important determinants of quality of life in Parkinson's disease, and there is increasing interest in understanding the extent and role of non-motor symptoms in amyotrophic lateral sclerosis. We therefore reviewed what is known about non-motor symptoms in amyotrophic lateral sclerosis, using lessons from Parkinson's disease.
Topics & Concepts
Amyotrophic lateral sclerosisParkinson's diseaseMedicineDiseasePhysical medicine and rehabilitationMotor symptomsMotor neurone diseaseNeurosciencePsychologyPathologyParkinson's Disease Mechanisms and TreatmentsAmyotrophic Lateral Sclerosis ResearchNeurological diseases and metabolism