<i>meta</i> -Selective thiofluoroalkylation of substituted pyridines <i>via</i> Zincke imines
Will C. Hartley, A. Huerta, Júlia C. Negredo, Omar Boutureira
Abstract
meta -C–H bonds in pyridines were replaced with thiopolyfluoroalkyl motifs using Zincke imines and saccharine-based reagents.
Topics & Concepts
ChemistryCombinatorial chemistryOrganic chemistryFluorine in Organic ChemistryCyclopropane Reaction MechanismsSynthesis and Reactions of Organic Compounds