Hydrogen-Substituted Graphdiyne Encapsulated Cu<sub>2</sub>O Nanowires as Binder-Free Electrodes for Non-Enzymatic Glucose Sensing
Chellamuthu Jeganathan, Hibiki Mitsuboshi, Hikaru Yamamoto, Yukihiro Motoyama, Kenta Kokado, Masanori Hara, Masamichi Yoshimura
Abstract
The fabrication of electrochemical biosensors without any binder or enzymes is in high demand in the clinical diagnostic and industrial sectors. This work presents the development of hydrogen-substituted graphdiyne encapsulated Cu 2 O nanowires (Cu 2 O NWs@ HsGDY) hybrid electrode, directly grown on Cu foils. The sp and sp 2 hybridization of HsGDY is confirmed by Raman and X-ray photoelectron spectroscopy, and the HsGDY encapsulation over Cu 2 O NWs is observed in transmission electron microscope images. The fabricated binder-free, nonenzymatic electrode exhibits the highest sensitivity of 584.2 μA·cm 2 ·μM –1 (Cu 2 O NWs@HsGDY-1 h), the lowest detection limits of 0.035 μM (Cu 2 O NWs@HsGDY-6 h) and a linear detection range of 0.5–2500 μM. The Cu 2 O NWs@HsGDY-6 h electrode demonstrates 70 days of stability (82%) and excellent reproducibility (RSD = 1.97%) compared to other hybrid electrodes. The improved glucose sensing performance and stability is a combined effect of semiconducting nature and catalytic ability are attributed to Cu 2 O NWs@HsGDY hybrid electrodes. The successful glucose detection in actual food samples indicates the practical applicability of the Cu 2 O NWs@HsGDY sensor.