Litcius/Paper detail

IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor

Keishi Adachi, Yosuke Kano, Tomohiko Nagai, Namiko Okuyama, Yukimi Sakoda, Koji Tamada

2018Nature Biotechnology778 citationsDOI

Topics & Concepts

Chimeric antigen receptorCCL19Immune systemInfiltration (HVAC)T cellCancer researchInterleukin 21IL-2 receptorBiologyImmunologyChemokineChemokine receptorMaterials scienceComposite materialCAR-T cell therapy researchVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects