The catalytic role of elemental sulfur in the DMSO-promoted oxidative coupling of methylhetarenes with amines: synthesis of thioamides and bis-aza-heterocycles
Thi Thu Tram Nguyen, Thi Thu Tram Nguyen, Le Anh Nguyen, Quoc Anh Ngo, Marina Koleski, Thanh Binh Nguyen, Thanh Binh Nguyen
Abstract
The S<sub>8</sub>/DMSO combination was found to be particularly effective to promote oxidative coupling of methylhetarenes with amines to synthesize thioamides/bis-aza-heterocycles.
Topics & Concepts
ChemistryOxidative coupling of methaneSulfurOxidative phosphorylationCatalysisCombinatorial chemistryOrganic chemistryMedicinal chemistryBiochemistrySulfur-Based Synthesis TechniquesSynthesis of heterocyclic compoundsSynthesis and Reactivity of Sulfur-Containing Compounds