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Expanding screening through the use of liquid biopsy for early cancer detection

Marta Perachino, Carolina Ortiz, Javier Carmona, Cristina Saura, Ana Vivancos

2025Communications Medicine8 citationsDOIOpen Access PDF

Abstract

Screening programs have helped reduce cancer-specific mortality by detecting cancer at earlier stages. Developing increasingly sensitive, organ-specific liquid biopsy assays to evaluate tumor-derived analytes could pave the way for non-invasive early cancer diagnosis in population screening programs. Perachino et al. discuss screening through the use of liquid biopsy for early cancer detection. They emphasize the need for exceptionally high sensitivity and specificity when implementing such programs in the general population.

Topics & Concepts

Liquid biopsyCancer detectionMedicineBiopsyCancer screeningCancerMedical physicsRadiologyInternal medicineCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsAI in cancer detection
Expanding screening through the use of liquid biopsy for early cancer detection | Litcius