Litcius/Paper detail

Naturally Occurring Partially Reduced Perylenequinones from Fungi

Regina Geris, Matheus A. Pinho, Elisangela Fabiana Boffo, Thomas J. Simpson

2022Journal of Natural Products14 citationsDOIOpen Access PDF

Abstract

This Review provides a critical analysis of the literature covering the naturally occurring partially reduced perylenequinones (PQs) from fungi without carbon substituents (which can be named class A perylenequinones) and discusses their structures, stereochemistry, biosynthesis, and biological activities as appropriate. Perylenequinones are natural pigments with a perylene skeleton produced by certain fungi, aphids, some plants, and animal species. These compounds display several biological activities, e.g., antimicrobial, anti-HIV, photosensitizers, cytotoxic, and phytotoxic. It describes 36 fungal PQs and cites 81 references, covering from 1956 to August 2022.

Topics & Concepts

AntimicrobialBiological activityCarbon skeletonBotanyPeryleneBiologyStereochemistryChemistryAntifungalOrganic chemistryBiochemistryMicrobiologyIn vitroMoleculeMicrobial Natural Products and BiosynthesisEssential Oils and Antimicrobial ActivityFungal Biology and Applications