C(sp<sup>3</sup>)–H/C(sp<sup>3</sup>)–H Dehydrogenative Radical Coupling of Glycine Derivatives
Jiayuan Wang, Youwan Ye, Tongzhi Sang, Chenxing Zhou, Xiazhen Bao, Yong Yuan, Congde Huo
Abstract
)-H dehydrogenative coupling strategy for the preparation of various natural or unnatural amino acids from readily available glycine derivatives and hydrocarbons through a combination of SET and HAT process.
Topics & Concepts
ChemistryGlycineMedicinal chemistryCoupling (piping)StereochemistryAmino acidCombinatorial chemistryBiochemistryEngineeringMechanical engineeringRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques