Design, synthesis, and in vitro and in vivo anti-angiogenesis study of a novel vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor based on 1,2,3-triazole scaffold
De-pu Wang, Kai-li Liu, Xinyang Li, Guoqing Lu, Wen-han Xue, Xin-hua Qian, Kamara Mohamed Olounfeh, Fan‐hao Meng
Topics & Concepts
SunitinibChemistryAngiogenesisIn vivoUmbilical veinVascular endothelial growth factorDocking (animal)Kinase insert domain receptorPharmacologyIn vitroBiochemistryVascular endothelial growth factor ACancer researchVEGF receptorsBiologyMedicineCancerBiotechnologyNursingGeneticsAngiogenesis and VEGF in CancerCAR-T cell therapy researchClick Chemistry and Applications