A near-infrared fluorescence probe for imaging of pantetheinase in cells and mice <i>in vivo</i>
Yuantao Yang, Yiming Hu, Wen Shi, Huimin Ma
Abstract
. Moreover, with the probe we have observed that pantetheinase is significantly increased in the tissues of mouse inflammatory models as well as in the intestines of mice with inflammatory bowel disease. Therefore, CYLP may provide a convenient and intuitive tool for studying the role of pantetheinase in diseases.
Topics & Concepts
FluorescenceIn vivoFluorescence-lifetime imaging microscopyInfraredInflammatory bowel diseasePreclinical imagingChemistryPathologyBiophysicsBiomedical engineeringMedicineBiologyOpticsDiseasePhysicsBiotechnologyRNA regulation and diseaseNeurological diseases and metabolismTrace Elements in Health