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S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome

Yihui Yang, Li Wan, Liwen Ren, Hong Yang, Yizhi Zhang, Sen Zhang, Hao Yue, Dongke Yu, Rongsheng Tong, Guanhua Du, Jianyou Shi, Jinhua Wang

2023Acta Pharmacologica Sinica16 citationsDOIOpen Access PDF

Topics & Concepts

AutophagosomeAutophagyLysosomeCancer researchChemistryTemozolomideProgrammed cell deathU87Cell biologyCell cultureCell growthBiologyApoptosisBiochemistryGlioblastomaEnzymeGeneticsFerroptosis and cancer prognosisCancer-related molecular mechanisms researchCircular RNAs in diseases
S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome | Litcius