p38 inhibition enhances TCR-T cell function and antagonizes the immunosuppressive activity of TGF-β
Siyin Chen, Jing Zhang, Meiying Shen, Xiaojian Han, Shenglong Li, Chao Hu, Wang Wang, Li Luo, Li Du, Da Pang, Kun Tao, Aishun Jin
Topics & Concepts
Granzyme BCell biologyT cellT-cell receptorGranzymeBiologyIL-2 receptorCytotoxic T cellCancer researchPerforinImmunologyAntigenChemistryCD8Immune systemBiochemistryIn vitroCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology