A unifying model of glucotoxicity in human renal proximal tubular epithelial cells and the effect of the SGLT2 inhibitor dapagliflozin
Theodoros Eleftheriadis, Georgios Pissas, Konstantina Tsogka, Evdokia Nikolaou, Vassilios Liakopoulos, Ioannis Stefanidis
Topics & Concepts
MethylglyoxalDapagliflozinInternal medicineEndocrinologyGlycationPolyol pathwayBiochemistryChemistryMedicineDiabetes mellitusType 2 diabetesEnzymeAldose reductaseAdvanced Glycation End Products researchChronic Kidney Disease and DiabetesGlycosylation and Glycoproteins Research