Dietary polyphenols mitigate SARS-CoV-2 main protease (Mpro)–Molecular dynamics, molecular mechanics, and density functional theory investigations
Temitope Isaac Adelusi, Abdul-Quddus Kehinde Oyedele, Ojo Emmanuel Monday, Ibrahim Damilare Boyenle, Mukhtar Oluwaseun Idris, Abdeen Tunde Ogunlana, Ashiru Mojeed Ayoola, John Olabode Fatoki, Oladipo Elijah Kolawole, Kehinde Busuyi David, Akintola Adebola Olayemi
Topics & Concepts
Ellagic acidChemistryDocking (animal)PolyphenolMolecular mechanicsAutoDockProteaseVirtual screeningMolecular dynamicsDrug discoveryCoronavirusBinding affinitiesBiochemistryStereochemistryCombinatorial chemistryComputational biologyCoronavirus disease 2019 (COVID-19)PharmacologyEnzymeComputational chemistryInfectious disease (medical specialty)AntioxidantDiseaseBiologyVeterinary medicineReceptorGeneIn silicoMedicinePathologyComputational Drug Discovery MethodsNigella sativa pharmacological applicationsEssential Oils and Antimicrobial Activity